(1993) Richard Roberts

Sir Richard John Roberts born 6 September 1943 in Derby, is a British biochemist and molecular biologist. He was awarded the 1993 Nobel Prize in Physiology or Medicine with Phillip Allen Sharp for the discovery of introns in eukaryotic DNA and the mechanism of gene-splicing. In 1965 he graduated from the University of Sheffield with a Bachelor of Science degree in Chemistry followed by a PhD in 1969. His thesis involved phytochemical studies of neoflavonoids and isoflavonoids. During 1969?1972, he did postdoctoral research at Harvard University. before moving to Cold Spring Harbor Laboratory, where he was hired by James Dewey Watson, a co-discoverer of the structure of DNA and a fellow Nobel laureate. In this period he also visited the MRC Laboratory of Molecular Biology for the first time, working alongside Fred Sanger.[15] In 1977, he published his discovery of RNA splicing. In 1992, he moved to New England Biolabs. The following year, he shared a Nobel Prize with his former colleague at Cold Spring Harbor Phillip Allen Sharp.
Roberts\'s discovery of the alternative splicing of genes, in particular, has had a profound impact on the study and applications of molecular biology. The realisation that individual genes could exist as separate, disconnected segments within longer strands of DNA first arose in his 1977 study of adenovirus, one of the viruses responsible for causing the common cold. Robert\'s research in this field resulted in a fundamental shift in our understanding of genetics, and has led to the discovery of split genes in higher organisms, including human beings.
dodano dnia: 2023-04-06 10:47:13